which is better semaglutide or tirzepatide reddit than 🚀 vs vs Retatrutide: Fat Loss & Safety Comparison (2026 Fridays | GLP-1 Telehealth |

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Tirzepatide has shown even greater efficacy, with some patients losing up to 20% of their body weight

Even the FDA acknowledged that "patients and prescribers may still see intermittent and limited localized supply disruptions as the products move through the supply chain from the manufacturer and distributors to local pharmacies." The American Society of Health-System Pharmacists' shortage list continues to show both semaglutide and tirzepatide injection in shortage

These include: It's important to note that the gastrointestinal side effects of semaglutide can often be minimized by starting at a low dose and gradually increasing it over time